texts:psilocybin_for_treating_depression
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| - | Magic Mushrooms May ‘Reset’ Brains of | + | Magic Mushrooms May ‘Reset’ Brains of Depressed Patients |
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| - | Depressed Patients | + | |
| Aim: To investigate the treatment of depression using psilocybin | Aim: To investigate the treatment of depression using psilocybin | ||
| Method: | Method: | ||
| + | |||
| 20 patients with a treatment-resistant form of the disorder. | 20 patients with a treatment-resistant form of the disorder. | ||
| + | |||
| Given two doses of psilocybin (10 mg and 25 mg), with the second dose a | Given two doses of psilocybin (10 mg and 25 mg), with the second dose a | ||
| week after the first. | week after the first. | ||
| + | |||
| Nineteen of these underwent initial brain imaging and then the second scan | Nineteen of these underwent initial brain imaging and then the second scan | ||
| one day after the high dose treatment. | one day after the high dose treatment. | ||
| + | |||
| Used two main brain imaging methods to measure changes in blood flow | Used two main brain imaging methods to measure changes in blood flow | ||
| and the crosstalk between brain regions. (fMRI) | and the crosstalk between brain regions. (fMRI) | ||
| + | |||
| Patients reported their depressive symptoms through completing clinical | Patients reported their depressive symptoms through completing clinical | ||
| questionnaires. | questionnaires. | ||
| Results: | Results: | ||
| + | |||
| fMRI imaging revealed reduced blood flow in areas of the brain, | fMRI imaging revealed reduced blood flow in areas of the brain, | ||
| including the amygdala, a small, almond-shaped region of the brain | including the amygdala, a small, almond-shaped region of the brain | ||
| known to be involved in processing emotional responses, stress, and fear. | known to be involved in processing emotional responses, stress, and fear. | ||
| + | |||
| We have shown for the first time clear changes in brain activity in | We have shown for the first time clear changes in brain activity in | ||
| depressed people treated with psilocybin after failing to respond to | depressed people treated with psilocybin after failing to respond to | ||
| conventional treatments. | conventional treatments. | ||
| + | |||
| Psilocybin may be giving these individuals the temporary ‘kick start’ they | Psilocybin may be giving these individuals the temporary ‘kick start’ they | ||
| need to break out of their depressive states. | need to break out of their depressive states. | ||
| + | |||
| + | {{:texts:depression-magic-mushroom-neurosciencenews.jpg?400|}} | ||
| Conclusion: | Conclusion: | ||
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| The psychedelic compound may effectively reset the activity of key brain | The psychedelic compound may effectively reset the activity of key brain | ||
| circuits known to play a role in depression. | circuits known to play a role in depression. | ||
| + | |||
| However many other implications can be drawn and highlighted about | However many other implications can be drawn and highlighted about | ||
| drug use. As the authors warn “while the initial findings are encouraging, | drug use. As the authors warn “while the initial findings are encouraging, | ||
| Line 43: | Line 53: | ||
| Imperial College London “Magic Mushrooms May ‘Reset’ Brains of Depressed | Imperial College London “Magic Mushrooms May ‘Reset’ Brains of Depressed | ||
| Patients.” NeuroscienceNews. NeuroscienceNews, 12 October 2017. | Patients.” NeuroscienceNews. NeuroscienceNews, 12 October 2017. | ||
| - | <http://neurosciencenews.com/magic-mushrooms- depression-7734/>. | + | <http://neurosciencenews.com/magic-mushrooms-may-reset-brains-depressed-patients/ |
texts/psilocybin_for_treating_depression.1511692515.txt.gz · Last modified: 2017/11/26 10:35 by nm
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